This data table contains the processed data for the LacI genotype-phenotype landscape, a quantitative measurement of the phenotype for approximately 60,000 variants of the E. coli LacI protein. The table includes, for example, the DNA barcode sequencing counts and the estimated fitness for each variant across 24 different chemical environments. It also includes the estimated dose-response curves for each variant under induction with IPTG.
About this Dataset
Title | LacI protein genotype-phenotype landscape data |
---|---|
Description | This data table contains the processed data for the LacI genotype-phenotype landscape, a quantitative measurement of the phenotype for approximately 60,000 variants of the E. coli LacI protein. The table includes, for example, the DNA barcode sequencing counts and the estimated fitness for each variant across 24 different chemical environments. It also includes the estimated dose-response curves for each variant under induction with IPTG. |
Modified | 2020-06-30 00:00:00 |
Publisher Name | National Institute of Standards and Technology |
Contact | mailto:[email protected] |
Keywords | allostery , E. coli , Lac repressor , fitness landscape , genotype-phenotype relationships , DNA barcode sequencing , engineering biology |
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