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71 results found

NIST DART-MS Forensics Database (is-CID)

Data provided by  National Institute of Standards and Technology

The NIST DART-MS Forensics Database is an evaluated collection of in-source collisionally-induced dissociation (is-CID) mass spectra of compounds of interest to the forensics community (e.g. seized drugs, cutting agents, etc.). The is-CID mass spectra were collected using Direct Analysis in Real-Time (DART) Mass Spectrometry (MS), either by NIST scientists or by contributing agencies noted per compound. The database is provided as a general-purpose structure data file (.SDF).

Tags: Standard reference data,mass spectra,Ion Fragmentation,mass spectrometry,NIST Mass Spectral Libraries,Chemical Identification,Biosciences and Health,Security and Forensics,

Modified: 2024-02-22

Views: 0

RGTM 10169

Data provided by  National Institute of Standards and Technology

NIST developed a reference material consisting of synthetic fragments of the SARS-CoV-2 virus RNA, which is the target of molecular diagnostic tests. These RNA fragments can assist in the development and validation of RT-qPCR assays for the detection SARS-CoV-2. The RNA fragments are characterized for concentration using digital PCR methods, may be used to assess limits of detection for SARS-CoV-2 assays, and may calibrate other in-house or commercial SARS-CoV-2 controls. This dataset includes data used for RTGM 10169 SARs-Cov-2 Research Grade Test Material validation.

Tags: virus,SRM,reference material,DNA,sequencing,PCR,digital PCR,Biosciences and Health,

Modified: 2024-02-22

Views: 0

NMR Interlaboratory Study of NISTmAb

Data provided by  National Institute of Standards and Technology

The NISTmAb Interlaboratory NMR Study is a joint effort between 25 organizations to evaluate the performance of two-dimensional (2D) heteronuclear NMR as used to characterize the high order structure (HOS) of proteins, with the aim of harmonizing 2D-NMR methods to support industrial use of NMR as applied to mAb therapeutics. This study features nearly equal representation between laboratories from academia, government, and industry, including 4 laboratories from regulatory agencies.

Tags: NMR,biopharmaceuticals,structure,fingerprint,comparability,biosimilarity,NISTmAb,RM 8671,Biosciences and Health,interlaboratory study,harmonization,chemometrics,

Modified: 2024-02-22

Views: 0

Datasets from an interlaboratory comparison to characterize a multi-modal polydisperse sub-micrometer bead dispersion

Data provided by  National Institute of Standards and Technology

These four data files contain datasets from an interlaboratory comparison that characterized a polydisperse five-population bead dispersion in water. A more detailed version of this description is available in the ReadMe file (PdP-ILC_datasets_ReadMe_v1.txt), which also includes definitions of abbreviations used in the data files. Paired samples were evaluated, so the datasets are organized as pairs associated with a randomly assigned laboratory number.

Tags: Biosciences and Health,particle,protein particle,sub-micrometer particle,subvisible particle,particle tracking analysis,resonant mass measurement,electrical sensing zone,holographic particle characterization,flow imaging,laser diffraction,flow cytometry,

Modified: 2024-02-22

Views: 0

Aggregation of Purified Protein Reference Materials Characterized by Asymmetric Flow Field Flow Fractionation

Data provided by  National Institute of Standards and Technology

This is a file containing aggregation data for two proteins that were thermomechanically aggregated. The aggregated proteins were separated by asymmetric flow field flow fractionation and separated protein fractions were detected and quantified by UV spectrophotometry and multi-angle light scattering. The UV spectrophotometry was used to quantify the amount of residual monomer, which is reported herein. The multi-angle light scattering was fitted to a relevant model to calculate the molecular weight of the aggregated protein, also reported herein.

Tags: electrical sensing zone,flow imaging,light obscuration,particle,protein aggregate,protein particle,subvisible particle,visible particle,Biosciences and Health,

Modified: 2024-02-22

Views: 0

SRM 3163 Tungsten (W) Standard Solution, Lot No. 140606

Data provided by  National Institute of Standards and Technology

This Standard Reference Material (SRM) is intended for use as a primary calibration standard for the quantitative determination of tungsten. A unit of SRM 3163 consists of 50 mL of an acidified aqueous solution prepared gravimetrically to contain a known mass fraction of tungsten in a high-density polyethylene bottle sealed in an aluminized bag.

Tags: tungsten,pure materials,cations,single-element solutions,spectrometry,Biosciences and Health,

Modified: 2024-02-22

Views: 0

SRM 3180 Iodide Anion (I-) Standard Solution

Data provided by  National Institute of Standards and Technology

This Standard Reference Material (SRM) is intended for use as a primary calibration standard for the quantitative determination of iodide. A unit of SRM 3180 consists of five 5 mL, sealed, amber, borosilicate glass ampoules of solution prepared gravimetrically to contain a known mass fraction of iodide. The matrix of the solution is water containing sodium sulfite at a concentration of approximately 0.01 mol/L and sodium hydroxide at a concentration of approximately 0.005 mol/L. This data is public in the Certificate of Analysis for this material.

Tags: Standard Reference Material,SRM,iodide,anion,Advanced Materials,

Modified: 2024-02-22

Views: 0

SRM 3181 Sulfate Anion (SO42-) Standard Solution

Data provided by  National Institute of Standards and Technology

This Standard Reference Material (SRM) is intended for use as a primary calibration standard for the quantitative determination of sulfate using anion ion chromatography (IC) or other methods. A unit of SRM 3181 consists of five 10 mL sealed borosilicate glass ampoules of solution prepared gravimetrically to contain a known mass fraction of sulfate dissolved in filtered (0.22 ?m) water having a minimum resistivity of 18 megaohm centimeters. This data is public in the Certificate of Analysis for this material.

Tags: Standard Reference Material,SRM,sulfate,anion,Advanced Materials,

Modified: 2024-02-22

Views: 0

SRM 3182 Chloride Anion (Cl-) Standard Solution

Data provided by  National Institute of Standards and Technology

This Standard Reference Material (SRM) is intended as a primary standard for the quantitative determination of chloride using anion ion chromatography (IC) or other methods. A unit of SRM 3182 consists of five 10 mL sealed borosilicate glass ampoules of solution. The solution is prepared gravimetrically to contain a known mass fraction of chloride dissolved in filtered (0.22 µm) water having a minimum resistivity of 18 megaohm centimeters. This data is public in the Certificate of Analysis for this material.

Tags: Standard Reference Material,SRM,chloride,anion,Advanced Materials,

Modified: 2024-02-22

Views: 0

SRM 3183 Fluoride Anion (F-) Standard Solution

Data provided by  National Institute of Standards and Technology

This Standard Reference Material (SRM) is intended as a primary calibration standard for the quantitative determination of fluoride using anion ion chromatography (IC) or other methods. A unit of SRM 3183 consists of 50 mL of solution in a high density polyethylene bottle sealed in an aluminized bag. The solution is prepared gravimetrically to contain a known mass fraction of fluoride dissolved in filtered (0.22 µm) water having a minimum resistivity of 18 megaohm centimeters. This data is public in the Certificate of Analysis for this material.

Tags: Standard Reference Material,SRM,fluoride,anion,Advanced Materials,

Modified: 2024-02-22

Views: 0