The NIST DART-MS Forensics Database is an evaluated collection of in-source collisionally-induced dissociation (is-CID) mass spectra of compounds of interest to the forensics community (e.g. seized drugs, cutting agents, etc.). The is-CID mass spectra were collected using Direct Analysis in Real-Time (DART) Mass Spectrometry (MS), either by NIST scientists or by contributing agencies noted per compound. The database is provided as a general-purpose structure data file (.SDF).

NIST developed a reference material consisting of synthetic fragments of the SARS-CoV-2 virus RNA, which is the target of molecular diagnostic tests. These RNA fragments can assist in the development and validation of RT-qPCR assays for the detection SARS-CoV-2. The RNA fragments are characterized for concentration using digital PCR methods, may be used to assess limits of detection for SARS-CoV-2 assays, and may calibrate other in-house or commercial SARS-CoV-2 controls. This dataset includes data used for RTGM 10169 SARs-Cov-2 Research Grade Test Material validation.

The NISTmAb Interlaboratory NMR Study is a joint effort between 25 organizations to evaluate the performance of two-dimensional (2D) heteronuclear NMR as used to characterize the high order structure (HOS) of proteins, with the aim of harmonizing 2D-NMR methods to support industrial use of NMR as applied to mAb therapeutics. This study features nearly equal representation between laboratories from academia, government, and industry, including 4 laboratories from regulatory agencies.

This curated dataset consists of 269,353 patent documents (published patent applications and granted patents) spanning the 1976 to 2016 period and is intended to help identify promising R&D on the horizon in diagnostics, therapeutics, data analytics, and model biological systems.

Contains Cooperative Patent Classification (CPC) classification information for all Utility patent applications published by the U.S. Patent and Trademark Office (USPTO) from 2001 to present. It is available as XML with schemas or text monthly (usually by the 15th of the month).

These four data files contain datasets from an interlaboratory comparison that characterized a polydisperse five-population bead dispersion in water. A more detailed version of this description is available in the ReadMe file (PdP-ILC_datasets_ReadMe_v1.txt), which also includes definitions of abbreviations used in the data files. Paired samples were evaluated, so the datasets are organized as pairs associated with a randomly assigned laboratory number.

Contains detailed information derived from the Office actions issued by patent examiners to applicants during the patent examination process. The Office Action is a written notification to the applicant of the examiners decision on patentability. It generally discloses the reasons for any rejections, objections, or requirements and includes relevant information or references that the applicant may find useful for responding to the examiner and deciding whether to continue prosecuting the application.

Contains detailed information derived from the Office actions issued by patent examiners to applicants during the patent examination process. The Office Action is a written notification to the applicant of the examiners decision on patentability. It generally discloses the reasons for any rejections, objections, or requirements and includes relevant information or references that the applicant may find useful for responding to the examiner and deciding whether to continue prosecuting the application.

Contains detailed information on 4.4 million Office actions mailed from 2008 through June 2017 for 2.2 million publicly viewable patent applications. The data are sourced from the text of Non-Final Rejection and Final Rejection Office Actions issued by patent examiners to applicants during the patent examination process. The data files include information on grounds for rejection raised, the claims in question, and pertinent prior art.

Contains four research datasets containing time series and micro-level data by National Bureau of Economic Research (NBER) technology sub-category on applications, grants, and in-force patents spanning two centuries of innovation.